Intraepithelial carcinoma (Bowen disease) - I-Intraepithelial Carcinoma (Isifo Se-Bowen)
☆ Emiphumeleni ka-2022 ye-Stiftung Warentest evela eJalimane, ukwaneliseka kwabathengi nge-ModelDerm bekungaphansi kancane kunokuxhumana okukhokhelwayo kwe-telemedicine.
Icala elijwayelekile ― I-Intraepithelial Carcinoma (Isifo Se-Bowen) (Intraepithelial carcinoma (Bowen disease)) ingase ingaziwa njenge-eczema ehlala isikhathi eside, engalumayo.
References
Bowen's disease (BD) wuhlobo lomdlavuza wesikhumba oluqala olwelwesini olungaphandle lwesikhumba (epidermis) . Kuvame kakhulu eCaucasus futhi kuvame ukuvela ezindaweni ezichayeke elangeni, kodwa kungavela nakwezinye izindawo. I-BD ngokuvamile ibonakala njengesilonda esisodwa. I-BD ivame ukubonwa njengophawu oluyisixwayiso ngaphambi kokuba kuvele uhlobo olubi kakhulu lomdlavuza wesikhumba. Ukuze uhlole i-BD, odokotela ngokuvamile bathembela ekuhloleni amasampula ezicubu ngaphansi kwesibonakhulu (i-biopsy) .
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease ihlasela kakhulu abantu abamhlophe abaneminyaka engaphezu kuka-60. Izinto eziyingozi eziyinhloko zihlanganisa ukuchayeka elangeni isikhathi eside, amasosha omzimba abuthakathaka, ukuchayeka kwe-arsenic, kanye nokutheleleka nge-HPV yesikhumba. Izinhlobo ze-HPV ezingu-16, 18, 34, no-48 zixhunyaniswa nesifo sika-Bowen ezindaweni zangasese. Ukubandakanyeka kwe-HPV ezimweni ezingezona ezobulili akucaci kahle.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Ivamise ukuvela njengendawo ebomvu tebhu, enezikhwepha noma ewuqweqwe noma kuphi emzimbeni. Indawo evame kakhulu imilenze ephansi.
Kwelapheka ngezinketho zokwelapha ezahlukahlukene ezifana ne-cryotherapy, i-curettage, i-cautery, i-photodynamic therapy, noma ukusika isilonda.
○ Ukuxilongwa Nokwelashwa
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy